Definition: a severe and frequently fatal septicemicpasteurellosis of cattle caused by Pasteurella multocidatype B:2 or E:2.
the condition is characterized by sudden severe pyrexia, dyspnea, salivation, hot and painful edematous skin
swellings, and submucosal petechiation.
Antimicrobials are effective against HS if administered very early in the disease. However, because HS progresses rapidly, therapy is often unsuccessful. During outbreaks, any animal with a fever should be treated with IV antimicrobials as soon as possible to quickly obtain systemic bactericidal antimicrobial concentrations. Various sulfonamides, tetracyclines, penicillin, gentamicin, kanamycin, ceftiofur, enrofloxacin, tilmicosin, and chloramphenicol have been used effectively to treat HS. However, plasmid- and chromosomal-mediated multidrug resistance seems to be increasing for some strains of P multocida, and resistance to tetracyclines and penicillin has been reported for serotype B:2.
Prevention is by vaccination twice yearly, preferably with the oil-adjuvant or alumprecipitated bacterin